Astronomers discover closest black hole to Earth

Black hole illustration

Astronomers using the International Gemini Observatory, operated by NSF's NOIRLab, have discovered the closest-known black hole to Earth. This is the first unambiguous detection of a dormant stellar-mass black hole in the Milky Way. Its close proximity to Earth, a mere 1600 light-years away, offers an intriguing target of study to advance our understanding of the evolution of binary systems.

Black holes are the most extreme objects in the Universe. Supermassive versions of these unimaginably dense objects likely reside at the centers of all large galaxies. Stellar-mass black holes -- which weigh approximately five to 100 times the mass of the Sun -- are much more common, with an estimated 100 million in the Milky Way alone. Only a handful have been confirmed to date, however, and nearly all of these are 'active' -- meaning they shine brightly in X-rays as they consume material from a nearby stellar companion, unlike dormant black holes which do not.

Astronomers using the Gemini North telescope on Hawai'i, one of the twin telescopes of the InternationalGemini Observatory, operated by NSF's NOIRLab, have discovered the closest black hole to Earth, which the researchers have dubbed Gaia BH1. This dormant black hole is about 10 times more massive than the Sun and is located about 1600 light-years away in the constellation Ophiuchus, making it three times closer to Earth than the previous record holder, an X-ray binary in the constellation of Monoceros. The new discovery was made possible by making exquisite observations of the motion of the black hole's companion, a Sun-like star that orbits the black hole at about the same distance as the Earth orbits the Sun.

"Take the Solar System, put a black hole where the Sun is, and the Sun where the Earth is, and you get this system," explained Kareem El-Badry, an astrophysicist at the Center for Astrophysics | Harvard & Smithsonianand the Max Planck Institute for Astronomy, and the lead author of the paper describing this discovery. "While there have been many claimed detections of systems like this, almost all these discoveries have subsequently been refuted. This is the first unambiguous detection of a Sun-like star in a wide orbit around a stellar-mass black hole in our Galaxy."

Though there are likely millions of stellar-mass black holes roaming the Milky Way Galaxy, those few that have been detected were uncovered by their energetic interactions with a companion star. As material from a nearby star spirals in toward the black hole, it becomes superheated and generates powerful X-rays and jets of material. If a black hole is not actively feeding (i.e., it is dormant) it simply blends in with its surroundings.

"I've been searching for dormant black holes for the last four years using a wide range of datasets and methods," said El-Badry. "My previous attempts -- as well as those of others -- turned up a menagerie of binary systems that masquerade as black holes, but this is the first time the search has borne fruit."

The team originally identified the system as potentially hosting a black hole by analyzing data from the European Space Agency's Gaia spacecraft. Gaia captured the minute irregularities in the star's motion caused by the gravity of an unseen massive object. To explore the system in more detail, El-Badry and his team turned to the Gemini Multi-Object Spectrograph instrument on Gemini North, which measured the velocity of the companion star as it orbited the black hole and provided precise measurement of its orbital period. The Gemini follow-up observations were crucial to constraining the orbital motion and hence masses of the two components in the binary system, allowing the team to identify the central body as a black hole roughly 10 times as massive as our Sun.

"Our Gemini follow-up observations confirmed beyond reasonable doubt that the binary contains a normal star and at least one dormant black hole," elaborated El-Badry. "We could find no plausible astrophysical scenario that can explain the observed orbit of the system that doesn't involve at least one black hole."

The team relied not only on Gemini North's superb observational capabilities but also on Gemini's ability to provide data on a tight deadline, as the team had only a short window in which to perform their follow-up observations.

"When we had the first indications that the system contained a black hole, we only had one week before the two objects were at the closest separation in their orbits. Measurements at this point are essential to make accurate mass estimates in a binary system," said El-Badry. "Gemini's ability to provide observations on a short timescale was critical to the project's success. If we'd missed that narrow window, we would have had to wait another year."

Astronomers' current models of the evolution of binary systems are hard-pressed to explain how the peculiar configuration of Gaia BH1 system could have arisen. Specifically, the progenitor star that later turned into the newly detected black hole would have been at least 20 times as massive as our Sun. This means it would have lived only a few million years. If both stars formed at the same time, this massive star would have quickly turned into a supergiant, puffing up and engulfing the other star before it had time to become a proper, hydrogen-burning, main-sequence star like our Sun.

It is not at all clear how the solar-mass star could have survived that episode, ending up as an apparently normal star, as the observations of the black hole binary indicate. Theoretical models that do allow for survival all predict that the solar-mass star should have ended up on a much tighter orbit than what is actually observed.

This could indicate that there are important gaps in our understanding of how black holes form and evolve in binary systems, and also suggests the existence of an as-yet-unexplored population of dormant black holes in binaries.

"It is interesting that this system is not easily accommodated by standard binary evolution models," concluded El-Badry. "It poses many questions about how this binary system was formed, as well as how many of these dormant black holes there are out there."

"As part of a network of space- and ground-based observatories, Gemini North has not only provided strong evidence for the nearest black hole to date but also the first pristine black hole system, uncluttered by the usual hot gas interacting with the black hole," said NSF Gemini Program Officer Martin Still. "While this potentially augurs future discoveries of the predicted dormant black hole population in our Galaxy, the observations also leave a mystery to be solved -- despite a shared history with its exotic neighbor, why is the companion star in this binary system so normal?"

 

Differences between brains of primates are small but significant, study shows

Model of brain 

 While the physical differences between humans and non-human primates are quite distinct, a new study reveals their brains may be remarkably similar. And yet, the smallest changes may make big differences in developmental and psychiatric disorders.

Understanding the molecular differences that make the human brain distinct can help researchers study disruptions in its development. A new study, published recently in the journal Science by a team including University of Wisconsin-Madison neuroscience professor Andre Sousa, investigates the differences and similarities of cells in the prefrontal cortex -- the frontmost region of the brain, an area that plays a central role in higher cognitive functions -- between humans and non-human primates such as chimpanzees, Rhesus macaques and marmosets.

The cellular differences between these species may illuminate steps in their evolution and how those differences can be implicated in disorders, such as autism and intellectual disabilities, seen in humans. Sousa, who studies the developmental biology of the brain at UW-Madison's Waisman Center, decided to start by studying and categorizing the cells in the prefrontal cortex in partnership with the Yale University lab where he worked as a postdoctoral researcher.

"We are profiling the dorsolateral prefrontal cortex because it is particularly interesting. This cortical area only exists in primates. It doesn't exist in other species," Sousa says. "It has been associated with several relevant functions in terms of high cognition, like working memory. It has also been implicated in several neuropsychiatric disorders. So, we decided to do this study to understand what is unique about humans in this brain region."

Sousa and his lab collected genetic information from more than 600,000 prefrontal cortex cells from tissue samples from humans, chimpanzees, macaques and marmosets. They analyzed that data to categorize the cells into types and determine the differences in similar cells across species. Unsurprisingly, the vast majority of the cells were fairly comparable.

"Most of the cells are actually very similar because these species are relatively close evolutionarily," Sousa says.

Sousa and his collaborators found five cell types in the prefrontal cortex that were not present in all four of the species. They also found differences in the abundancies of certain cell types as well as diversity among similar cell populations across species. When comparing a chimpanzee to a human the differences seem huge -- from their physical appearances down to the capabilities of their brains. But at the cellular and genetic level, at least in the prefrontal cortex, the similarities are many and the dissimilarities sparing.

"Our lab really wants to know what is unique about the human brain. Obviously from this study and our previous work, most of it is actually the same, at least among primates," Sousa says.

The slight differences the researchers found may be the beginning of determining some of those unique factors, and that information could lead to revelations about development and developmental disorders at a molecular level.

"We want to know what happened after the evolutionary split between humans and other primates," Sousa says. "The idea is you have a mutation in a gene or in several genes and those genes now have slightly different functions. But if these genes are relevant for brain development, for example, how many of a certain cell is produced, or how cells are connecting to other cells, how is it affecting the neuronal circuitry and their physiological properties? We want to understand how these differences lead to differences in the brain and then lead to differences we can observe in adults."

The study's observations were made in the brains of adults, after much of the development is complete. This means that the differences may be occurring during the brain's development. So, the researchers' next step is to study samples from developing brains and extend their area of investigation past the prefrontal cortex to potentially find where and when these differences originate. The hope is that this information will lead to a more robust foundation to lay developmental disorder research on top of.

"We are able to do extraordinary things, right? We are studying life itself, the universe, and so much more. And this is really unique when you look around," says Sousa, whose team included graduate students Ryan Risgaards and Zachary Gomez-Sanchez, research intern Danielle Schmidt, and undergraduate students Ashwin Debnath and Cade Hottman. "If we have these unique abilities, it has to be something in the brain, right? There is something in the brain that allows us to do all of that and we are really interested in knowing what it is."

Honey bee life spans are 50 percent shorter today than they were 50 years ago

Honey bees

 A new study by University of Maryland entomologists shows that the lifespan for individual honey bees kept in a controlled, laboratory environment is 50% shorter than it was in the 1970s. When scientists modeled the effect of today's shorter lifespans, the results corresponded with the increased colony loss and reduced honey production trends seen by U.S. beekeepers in recent decades.

Colony turnover is an accepted factor in the beekeeping business, as bee colonies naturally age and die off. But over the past decade, U.S. beekeepers have reported high loss rates, which has meant having to replace more colonies to keep operations viable. In an effort to understand why, researchers have focused on environmental stressors, diseases, parasites, pesticide exposure and nutrition.

This is the first study to show an overall decline in honey bee lifespan potentially independent of environmental stressors, hinting that genetics may be influencing the broader trends seen in the beekeeping industry. The study was published November 14, 2022, in the journal Scientific Reports.

"We're isolating bees from the colony life just before they emerge as adults, so whatever is reducing their lifespan is happening before that point," said Anthony Nearman, a Ph.D. student in the Department of Entomology and lead author of the study. "This introduces the idea of a genetic component. If this hypothesis is right, it also points to a possible solution. If we can isolate some genetic factors, then maybe we can breed for longer-lived honey bees."

Nearman first noticed the decline in lifespan while conducting a study with entomology associate professor Dennis van Engelsdorp on standardized protocols for rearing adult bees in the laboratory. Replicating earlier studies, the researchers collected bee pupae from honey bee hives when the pupae were within 24 hours of emerging from the wax cells they are reared in. The collected bees finished growing in an incubator and were then kept as adults in special cages.

Nearman was evaluating the effect of supplementing the caged bees' sugar water diet with plain water to better mimic natural conditions when he noticed that, regardless of diet, the median lifespan of his caged bees was half that of caged bees in similar experiments in the 1970s. (17.7 days today versus 34.3 days in the 1970s.) This prompted a deeper review of published laboratory studies over the past 50 years.

"When I plotted the lifespans over time, I realized, wow, there's actually this huge time effect going on," Nearman said. "Standardized protocols for rearing honey bees in the lab weren't really formalized until the 2000s, so you would think that lifespans would be longer or unchanged, because we're getting better at this, right? Instead, we saw a doubling of mortality rate."

Although a laboratory environment is very different from a colony, historical records of lab-kept bees suggest a similar lifespan to colony bees, and scientists generally assume that isolated factors that reduce lifespan in one environment will also reduce it in another. Previous studies had also shown that in the real world, shorter honey bee lifespans corresponded to less foraging time and lower honey production. This is the first study to connect those factors to colony turnover rates.

When the team modeled the effect of a 50% reduction in lifespan on a beekeeping operation, where lost colonies are replaced annually, the resulting loss rates were around 33%. This is very similar to the average overwinter and annual loss rates of 30% and 40% reported by beekeepers over the past 14 years.

Nearman and vanEngelsdorp noted that their lab-kept bees could be experiencing some sort of low-level viral contamination or pesticide exposure during their larval stage, when they're brooding in the hive and worker bees are feeding them. But the bees have not shown overt symptoms of those exposures and a genetic component to longevity has been shown in other insects such as fruit flies.

The next steps for the researchers will be to compare trends in honey bee lifespans across the U.S. and in other countries. If they find differences in longevity, they can isolate and compare potential contributing factors such as genetics, pesticide use and presence of viruses in the local bee stocks.

Oldest evidence of the controlled use of fire to cook food, researchers report

Wood fire burning

A remarkable scientific discovery has been made by researchers from the Hebrew University of Jerusalem (HU), Tel Aviv University (TAU), and Bar-Ilan University (BIU), in collaboration with the Steinhardt Museum of Natural History, Oranim Academic College, the Israel Oceanographic and Limnological Research (IOLR) institution, the Natural History Museum in London, and the Johannes Gutenberg University in Mainz. A close analysis of the remains of a carp-like fish found at the Gesher Benot Ya'aqov (GBY) archaeological site in Israel shows that the fish were cooked roughly 780,000 years ago. Cooking is defined as the ability to process food by controlling the temperature at which it is heated and includes a wide range of methods. Until now, the earliest evidence of cooking dates to approximately 170,000 years ago. The question of when early man began using fire to cook food has been the subject of much scientific discussion for over a century. These findings shed new light on the matter and was published in Nature Ecology and Evolution.

The study was led by a team of researchers: Dr. Irit Zohar, a researcher at TAU's Steinhardt Museum of Natural History and curator of the Beit Margolin Biological Collections at Oranim Academic College, and HU Professor Naama Goren-Inbar, director of the excavation site. The research team also included Dr. Marion Prevost at HU's Institute of Archaeology; Prof. Nira Alperson-Afil at BIU's Department for Israel Studies and Archaeology; Dr. Jens Najorka of the Natural History Museum in London; Dr. Guy Sisma-Ventura of the Israel Oceanographic and Limnological Research Institute; Prof. Thomas Tütken of the Johannes Gutenberg University in Mainz and Prof. Israel Hershkovitz at TAU's Faculty of Medicine.

Dr. Zohar and Dr. Prevost: "This study demonstrates the huge importance of fish in the life of prehistoric humans, for their diet and economic stability. Further, by studying the fish remains found at Gesher Benot Ya'aqob we were able to reconstruct, for the first time, the fish population of the ancient Hula Lake and to show that the lake held fish species that became extinct over time. These species included giant barbs (carp like fish) that reached up to 2 meters in length. The large quantity of fish remains found at the site proves their frequent consumption by early humans, who developed special cooking techniques. These new findings demonstrate not only the importance of freshwater habitats and the fish they contained for the sustenance of prehistoric man, but also illustrate prehistoric humans' ability to control fire in order to cook food, and their understanding the benefits of cooking fish before eating it."

In the study, the researchers focused on pharyngeal teeth (used to grind up hard food such as shells) belonging to fish from the carp family. These teeth were found in large quantities at different archaeological strata at the site. By studying the structure of the crystals that form the teeth enamel (whose size increases through exposure to heat), the researchers were able to prove that the fish caught at the ancient Hula Lake, adjacent to the site, were exposed to temperatures suitable for cooking, and were not simply burned by a spontaneous fire.

Until now, evidence of the use of fire for cooking had been limited to sites that came into use much later than the GBY site -- by some 600,000 years, and ones most are associated with the emergence of our own species, homo sapiens.

Prof. Goren-Inbar added: "The fact that the cooking of fish is evident over such a long and unbroken period of settlement at the site indicates a continuous tradition of cooking food. This is another in a series of discoveries relating to the high cognitive capabilities of the Acheulian hunter-gatherers who were active in the ancient Hula Valley region. These groups were deeply familiar with their environment and the various resources it offered them. Further, it shows they had extensive knowledge of the life cycles of different plant and animal species. Gaining the skill required to cook food marks a significant evolutionary advance, as it provided an additional means for making optimal use of available food resources. It is even possible that cooking was not limited to fish, but also included various types of animals and plants."

Prof. Hershkovitz and Dr. Zohar note that the transition from eating raw food to eating cooked food had dramatic implications for human development and behavior. Eating cooked food reduces the bodily energy required to break down and digest food, allowing other physical systems to develop. It also leads to changes in the structure of the human jaw and skull. This change freed humans from the daily, intensive work of searching for and digesting raw food, providing them free time in which to develop new social and behavioral systems. Some scientists view eating fish as a milestone in the quantum leap in human cognitive evolution, providing a central catalyst for the development of the human brain. They claim that eating fish is what made us human. Even today, it is widely known that the contents of fish flesh, such as omega-3 fatty acids, zinc, iodine and more, contribute greatly to brain development.

The research team believe that the location of freshwater areas, some of them in areas that have long since dried up and become arid deserts, determined the route of the migration of early man from Africa to the Levant and beyond. Not only did these habitats provide drinking water and attracted animals to the area but catching fish in shallow water is a relatively simple and safe task with a very high nutritional reward.

The team posits that exploiting fish in freshwater habitats was the first step on prehistoric humans' route out of Africa. Early man began to eat fish around 2 million years ago but cooking fish -- as found in this study -- represented a real revolution in the Acheulian diet and is an important foundation for understanding the relationship between man, the environment, climate, and migration when attempting to reconstruct the history of early humans.

It should be noted that evidence of the use of fire at the site -- the oldest such evidence in Eurasia -- was identified first by BIU's Prof. Nira Alperson-Afil. "The use of fire is a behavior that characterizes the entire continuum of settlement at the site," she explained. "This affected the spatial organization of the site and the activity conducted there, which revolved around fireplaces." Alperson-Afil's research of fire at the site was revolutionary for its time and showed that the use of fire began hundreds of thousands of years before previously thought.

HU's Goren-Inbar added that the archaeological site of GBY documents a continuum of repeated settlement by groups of hunter-gatherers on the shores of the ancient Hula Lake which lasting tens of thousands of years. "These groups made use of the rich array of resources provided by the ancient Hula Valley and left behind a long settlement continuum with over 20 settlement strata," Goren-Inbar explained. The excavations at the site have uncovered the material culture of these ancient hominins, including flint, basalt, and limestone tools, as well as their food sources, which were characterized by a rich diversity of plant species from the lake and its shores (including fruit, nuts, and seeds) and by many species of land mammals, both medium-sized and large.

Dr. Jens Najorka of the Natural History Museum in London explained: "In this study, we used geochemical methods to identify changes in the size of the tooth enamel crystals, as a result of exposure to different cooking temperatures. When they are burnt by fire, it is easy to identify the dramatic change in the size of the enamel crystals, but it is more difficult to identify the changes caused by cooking at temperatures between 200 and 500 degrees Celsius. The experiments I conducted with Dr. Zohar allowed us to identify the changes caused by cooking at low temperatures. We do not know exactly how the fish were cooked but given the lack of evidence of exposure to high temperatures, it is clear that they were not cooked directly in fire, and were not thrown into a fire as waste or as material for burning."

 

New study reveals that exposure to outdoor artificial light at night is associated with an increased risk of diabetes

 A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that outdoor artificial light at night (LAN) is associated with impaired blood glucose control and an increased risk of diabetes, with more than 9 million cases of the disease in Chinese adults being attributed to LAN exposure. The study is by Dr Yu Xu and colleagues at the Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Exposure to artificial LAN at night is a ubiquitous environmental risk factor in modern societies. The intensity of urban light pollution has increased to the point that it not only affects residents of big cities, but also those in distant areas such as suburbs and forest parks that may be hundreds of kilometres from the light source. The authors note: "Despite over 80% of the world's population being exposed to light pollution at night, this problem has gained limited attention from scientists until recent years."

Earth's 24-hour day-night cycle has resulted in most organisms, including mammals, having an inbuilt circadian (roughly 24-hour) timing system which is adapted to the natural sequence of light and dark periods. Light pollution has been found to alter the circadian rhythm of insects, birds and other animals, resulting in premature death and loss of biodiversity.

Artificial LAN has also been implicated as a potential cause of metabolic dysregulation through altering the timing of food intake. Rats exposed to artificial LAN developed glucose intolerance, exhibiting elevated blood sugar and insulin. Another study found that mice exposed to nocturnal dim white light of minimal brightness for 4 weeks had increased body mass and reduced glucose tolerance compared to animals whose environment was completely dark at night, despite having roughly equivalent energy consumption and expenditure.

Associations have also been found between artificial LAN and health problems in humans. A study of night-shift workers found that those exposed to brighter LAN were more likely to have disrupted circadian rhythms, as well as a greater risk of coronary heart disease. Other research found that higher LAN exposure was associated with a 13% and 22% increase in the likelihood of being overweight and obese, respectively, while exposure to LAN in the bedroom was reported to be positively associated with the development of diabetes in elderly people.

The potential impact of outdoor artificial LAN was revealed by a study in South India which used satellite images to map light pollution and compared this with data on general health markers among adults across the region. With increasing LAN intensity, there were corresponding rises in average body mass index (BMI), systolic blood pressure and 'bad' (LDL) cholesterol levels in the exposed population.

Diabetes is a critical public health problem in China, and the onset and progression of the disease is largely governed by behavioural and environmental risk factors. The nation's rapid urbanisation and economic growth has resulted in a dramatic increase in urban lighting, and the number of people exposed to it. Those living in cities are prone to being shifted away from a natural 24-hour day-night cycle, to one of round-the-clock working and leisure time, often staying out late and being exposed to artificial LAN.

The study used data from the China Noncommunicable Disease Surveillance Study; a representative sample of the general population in China taken in 2010 across 162 sites across the country. A total of 98,658 adults participated, undergoing interviews to collect demographic, medical, household income, lifestyle, education and family history information. The mean age of participants was 42.7 years and around approximately half were women.

Body weight and height of participants were measured to calculate BMI, and blood samples were taken to obtain levels of both fasting and postprandial (after meal) serum glucose, as well as glycated haemoglobin (HbA1c). This is a form of glucose bound to haemoglobin in red blood cells which acts as a moving average of blood sugar over the previous 8 to 12 weeks.

Participants at each study site were assigned an average artificial outdoor LAN exposure level for that location using night-time low-light image data of the Earth's surface from the US Defense Meteorological Satellite Program (DMSP). Exposure levels were ordered from lowest to highest and grouped into five quintiles (groups of 20% from highest to lowest), with the median light intensity in the highest quintile being 69 times greater than in the lowest.

The intensity of outdoor LAN varied substantially across China, with most areas being exposed to low intensity light, while higher intensities converged on the Eastern coastal cities. Participants living in areas in the higher quintiles of outdoor LAN were more likely to be older, have a higher BMI and household income, and live in an urban area. In contrast, those in the lower quintile areas reported higher levels of physical activity but fewer years of education.

The study found that the highest quintile of LAN exposure was associated with a relative increase of 28% in the prevalence of diabetes than in the lowest quintile areas. Chronic exposure to residential outdoor LAN was positively associated with blood glucose levels, insulin resistance and diabetes prevalence, and inversely associated with beta cell function, even after adjusting for many important diabetes risk factors. On average, for every 42 people living in regions in the highest quintile of LAN exposure, there is one more case of diabetes that would not have occurred if those individuals had been living in areas in the lowest quintile. While the association between LAN exposure and diabetes might not be as strong as with better known risk factors, the ubiquity of outdoor artificial light means that the scale of population exposure is vast.

The researchers estimated that more than 9 million cases of diabetes in Chinese adults aged ?18 years could be attributed to outdoor LAN exposure; a figure expected to increase with accelerating urbanisation and the growing number of people migrating from China's countryside to its cities. The global nature and scale of this problem is illustrated by the fact that an estimated 83% of the world's population and more than 99% of those in the US and Europe live under light-polluted skies.

These findings contribute to a growing body of evidence suggesting that LAN is detrimental to health and demonstrate that it may be a potential novel risk factor for diabetes. The authors conclude that "further studies involving the direct measurement of individual exposure to LAN are needed to confirm whether its relationship with diabetes is a causal one."