Wednesday 8 April 2020

Cremaffin Syrup: Uses, Dose , Compositions & Side Effects


Cremaffin Syrup is a laxative and is mostly consumed to relieve constipation. This is why it is often used by older people who have a slow bowel movement or weak bowels. The medicine is manufactured by Abbott and is also used to provide relief in situations such as painful conditions of the rectum, constipation, stomach acid, painful conditions of the anus, increased water retention in intestines, empty bowels before colonoscopy etc.

Uses & Benefits of Cremaffin:

Some of the most common uses of the laxative Cremaffin Syrup that it helps prevents, improve, control, and treat include: 
    Emptying of the bowel before colonoscopy
    Increased water in intestines
    Cremaffin helps in Painful condition of the anus
    Painful conditions of the rectum
     Stomach acid neutralization
     Constipation
     Easier passage of stool 
   Cremaffin helps to Softening the stool
    Smoothening effect on stomach ulcer
    Indigestion and consequent heartburn or angina
    Relieving the pain in and around rectal/anal area
    Soothe stomach ulcers.

    Other than these uses, Cremaffin may also be prescribed by doctors for other purposes        such as cleansing and detox, or for minor operations of the colon.

Side Effects of Cremaffin:


Usually Cremaffin does not cause users to experience any side effects. However, sometimes patients may have hypersensitivity or may overdose, in which situations the possible side effects that one may experience after taking Cremaffin include:
    Abdominal cramps
    Abdominal discomfort
    Abdominal pain
    Appetite loss
    Dizziness
    Fatigue
    Inflammation
    Itching of skin
     Loose motions
    Muscle weakness
    Vomiting
In case, any of these side effects are experienced one must consult a doctor immediately. This is not an exhaustive list as other side effects may also be caused by the drug in specific cases. Severe side effects of Cremaffin are rare but it is advisable to seek medical attention in case one’s condition begins to deteriorate quickly.

Common Dose of Cremaffin:

In order to have the best benefits, Cremaffin laxative should be taken during bedtime with water. Always use a measuring cup for the correct dose. Take the medicine in equal intervals for better results. The medicine can be taken in the morning also but that depends on the condition of the patient which is why one should consult the doctor before using it.
The dosage is prescribed by the doctor based on one’s age and their condition. The most common dosage for adults is 7.5-15 ml and for child is 5-10ml. One should note that it is safe to mix this medicine with ice cream or yogurt to be given to children who might not want to take it otherwise. Don’t give the medicine to the people having the same condition
Missed Dose: If the patient forgot to take a dose then it is advisable to take it as soon as the patient notices. If the time for the next dose is close then skip the missed dose and resume the intake of the medicine as per dosing schedule. Don’t double dose the medicine to make up for the missed dose.

Overdose: Don’t consume the medicine more than prescribed. Taking extra dose may worsen the condition of the patient. If any side effect is experienced, immediately contact a doctor.

Composition and Nature of Cremaffin:

Cremaffin consists of liquid paraffin (1.25 ml), magnesium hydroxide or milk of magnesia (3.75 ml) and sodium picosulfate (3.33 mg) as active ingredients.
Cremaffin is a laxative in nature, and it helps assist bowel movements and softens the stool.
Liquid Paraffin: Also known as mineral oil or liquid petrolatum, liquid paraffin is used as a stool softener. It is also used in a combination with other medicines in skin care products to prevent dry skin. Liquid Paraffin is not recommended in children less than 3 years.
Magnesium Hydroxide: It is an inorganic chemical compound which helps in reducing stomach acid and increases water in the intestines. It is used as a laxative to get relive from constipation. It is also used as an antacid to get relieve from sour stomach, indigestion, and heartburn.
Sodium Picosulfate: It is a stimulant laxative which helps in cleaning the colon as a preparation for colonoscopy or surgery in adults.

      How Cremaffin Works?
Cremaffin works by stimulating the bowel muscles gently, which in turn increases peristalsis that helps, propel bowel contents out of one’s body. The Cremaffin medicine also lubricates and helps soften stool, helping easy passage.
The paraffin present in the formulation also aids the retention of water and fat in the stool. The milk of magnesia present in the formula also has an important role to play; it draws water into the intestine which then helps soften the stool. Sodium picosulfate stimulates the bowels and makes them work faster and effectively.
In addition to this, the Cremaffin helps neutralize stomach acid as well thereby being effective against certain situations of angina, and acid reflux or GERD.

How to use Cremaffin?

The Cremaffin should not be taken on an empty stomach as this can increase the chance of side effects like diarrhea. The instructions on the bottle, or the doctor’s advice should be followed and an overdose should be avoided. Cremaffin missed doses should be taken as soon as the patient is reminded of them, but not if the next scheduled dosage time is less than 12 hours away.

The Cremaffin Syrup is usually prescribed to patients as follows:

Adults: between 7.5 ml to 15 ml
Children below the age of 10 years: between 5 ml to 10 ml

When is Cremaffin prescribed?

Cremaffin is a medicine used for treating constipation, painful conditions of anus and stomach acid. It is a laxative that softens the stools and helps in emptying the bowels.
Constipation: Its ingredient liquid paraffin is effective in treating constipation in both adults and children. It softens and lubricates the stools that help it in passing through the bowel. This relieves constipation by making it easier for the stool to pass.
Softening of stool: The cremaffin goes through the faecal matter and softens the stools. The paraffin accelerates the osmosis and pours more liquid in the stool by making it soft. It activates the nerve fibres within the colon and reduces the pain caused due to hard stools in piles.
Indigestion and heartburn: Indigestion is a sign of an underlying problem like gastroesophageal reflux disease, ulcer rather than a condition on its own. It causes recurrent pain in the upper abdomen. The cremaffin has antacids that help in reducing acidity, heartburn, and indigestion.
Relieves pain in the rectal/anus area : Rectal bleeding is not necessarily serious. It may cause mild bleeding. One may experience few drops of blood in the stool. This is from haemorrhoids or a small scratch from a stool. Sometimes the bleeding may get serious causing blood clots or black stools.

 Precautions and Warning: When to avoid Cremaffin:
Before consuming Cremaffin one must consult a doctor to ensure that this medicine does not interact with any of the other medicines being consumed or if there are pre-existing conditions for which Cremaffin is not recommended.

Individuals with the following conditions must consult a doctor before taking Cremaffin Syrup:

Allergy to the ingredients of the drug
Anorexia
Appendicitis
Blockage of intestines
Breastfeeding women
Diarrhoea
Diverticulitis
Heart problem
Intolerance to fructose or galactose
Punctured bowel
Additionally, it is advisable that one must take the dosage as prescribed by the doctor and avoid excessive use. The drug must also not be used if one has withdrawal symptoms from benzodiazepine or alcohol. It is better to avoid operating heavy machinery or driving after taking Cremaffin as there may be unexpected bowel movement and consequent urgencies.

It must be noted that Cremaffin Syrup may cause hypersensitivity in patients who have the following cases:

Allergic conditions
Are below the age of 10
First trimester of pregnancy
Intestinal obstruction

To ensure the cremaffin Syrup works effectively on the patient, the following steps should be taken:

The dosage of the Cremaffin depends on the age and the condition of the patient. A doctor should be consulted in case a person has any queries, otherwise the instructions on the packaging should be followed.
Cremaffin should be taken with food and not on an empty stomach lest it cause any side effects.
When using Cremaffin, a patient should ensure that they are taking enough fluids to ensure that the medicine can do its job well.
Since the medication can lead to habit formation, it should be used carefully. Prolonged and everyday usage is not recommended since the patient can develop a dependency on the drug.
It is safe for pregnant women and lactating mothers to use this drug.

Suspension form of the cremaffin:

The cremaffin is a laxative that helps in curing constipation for a short period of time by making it easy for the stool to pass. It is used in treating the following conditions like constipation, indigestion and
easing the pain from anus discomfort.
The medicine should not be taken if the patient is suffering has an allergy from any of its components or is suffering from diarrhea, appendicitis and renal dysfunction. Patients should make the limited use of cremaffin as it is an overdose for a long duration can lead to the dependence of the medicine, diarrhea, and fluid imbalance. It should not be used in conditions of intestinal obstruction.

Medicines that should not be taken with Cremaffin

Patient must share with their doctor about their medical history and what all medicines they are taking currently. They must share with the doctor if are using drugs that make them sleepy, like sleeping pills, muscle relaxants, and anti-anxiety drugs. Cremaffin may interact with certain drugs and products, such as:
   Amoxicillin
   Digoxin
   Furosemide 
   Kalexate
   Ketoconazole
    Raltegravir
Taking these medicines along with Cremaffin can influence its therapeutic effect and increase the risk of side-effects. Patients should always consider their doctor before consuming any of these drugs.

Cremaffin Interactions:

A Cremaffin may interact with another medicine over a period of time which can change the desirable effects of the drug. In this way, it can increase the risk of side-effects or render the drug ineffective.

Cremaffin may interact with the following products and drugs:


    Amoxicillin
    Dolutegravir dutrebis
    Doxycycline
    Furosemide
    Kalexate
    Prednisolone
    Raltegravir

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